| Normal anion gap acidosis | |
|---|---|
| Classification and external resources | |
| ICD-10 | E87.2 |
| ICD-9 | 276.2 |
| DiseasesDB | 29144 |
In renal physiology, normal anion gap acidosis, and less precisely non-anion gap acidosis, is an acidosis that is not accompanied by an abnormally increased anion gap.
The most common etiology of normal anion gap acidosis is diarrhea with a renal tubular acidosis being a distant second .
The differential diagnosis of normal anion gap acidosis is relatively short (when compared to the differential diagnosis of acidosis):
It can be remembered with the mnemonic HARD-UP.[2]
As opposed to high anion gap acidosis (which involves increased organic acid production), normal anion gap acidosis involves either increased production of chloride (hyperchloremic acidosis) or increased excretion of bicarbonate.
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